It is difficult to make an artificial liver so a substitutive technology, like the dialysis machine, is being made. Which of the options is mostly considered in making such machines?

• A. Using hepatocytes to filter blood
• B. Using semi permeable membrane to filter plasma
• C. Using solutions of different organic and inorganic composition, just like dialysate, to filter blood
• D. Filtering the organic and inorganic components of the blood separately