1.

A one year old boy presented with hepatosplenomegaly and delayed milestones.The liver biopsy and bone marrow biopsy revealed presence of histiocytes with PAS-positive Diastase resistant material in the cytoplasm.Electron microscopic examination of these histiocytes is most likely to reveal the presence of:

A. Birbeck granules in the cytoplasm
B. Myelin figures in the cytoplasm
C. Parallel rays of tubular structures in lysosomes
D. Electron dense deposit in the mitochondria
Answer» D. Electron dense deposit in the mitochondria


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