A 4 year old boy was admitted with a history of abdominal pain and fever for two months,maculopapular rash for 10 days, and dry cough, dyspnea and wheezing for 3 days.On examination,liver and spleen were enlarged 4 cm and 3 cm respectively below the costal margin.His hemoglobin was 10.0g/dl,platelet count 37x109/L and total leukocyte count 70x109/L,which included 80% eosinophils.Bone marrow examination revealed a cellular marrow comprising 45% blasts and 34% eosinophils and eosinophilic precursors.The blasts stained negative for myeloperoxidase and non-specific esterase and were positive for CD19,CD10,CD22 and CD20.Which one of the following statements in not true about this disease?

• A. Peripheral blood eosinophilia may normalize with chemotherapy.
• B. Inv (16) is often detected in the blasts and the eosinophils.
• C. Eosinophils are not part of the neoplastic colon.
• D. t(5:1rearrangement may be detected in blasts.